Glra2 | glycine receptor, alpha 2 subunit

GeneMGI:95748

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

1Associated diseases

Expression examined in:46Adult tissues

63Embryo tissues

Phenotypes

Phy. System:



increased lymphocyte cell number	1 supporting dataset	Glra2^{tm1b(KOMP)Wtsi}	hemizygote	Early adult	9.08x10^-6
increased circulating amylase level	1 supporting dataset	Glra2^{tm1b(KOMP)Wtsi}	hemizygote	Early adult	2.56x10^-5
increased circulating fructosamine level	1 supporting dataset	Glra2^{tm1b(KOMP)Wtsi}	hemizygote	Early adult	1.12x10^-5
decreased monocyte cell number	1 supporting dataset	Glra2^{tm1b(KOMP)Wtsi}	hemizygote	Early adult	3.95x10^-6
decreased neutrophil cell number	2 supporting datasets	Glra2^{tm1b(KOMP)Wtsi}	hemizygote	Early adult	1.73x10^-5
decreased red blood cell distribution width	1 supporting dataset	Glra2^{tm1b(KOMP)Wtsi}	hemizygote	Early adult	3.08x10^-7
decreased mean corpuscular volume	1 supporting dataset	Glra2^{tm1b(KOMP)Wtsi}	hemizygote	Early adult	5.99x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Glra2.

Associated images

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Histopathology

There is no histopathology data found for Glra2.

IMPC related publications

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External links

No external links available for Glra2.

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*Glra2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Glra2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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