Gdf5 | growth differentiation factor 5
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton
13 No significant impact
6 Not tested
Data collections
Gene metrics:13Significant phenotypes
18Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased grip strength | 4 supporting datasets | Gdf5em1(IMPC)Bay | homozygote | Early adult | 1.83x10-38 | ||
| decreased lymphocyte cell number | 1 supporting dataset | Gdf5em1(IMPC)H | homozygote | Early adult | 5.62x10-5 | ||
| abnormal hindlimb morphology | 2 supporting datasets | Gdf5em1(IMPC)H | homozygote | Early adult | 1.1x10-23 | ||
| abnormal bone structure | 1 supporting dataset | Gdf5em1(IMPC)Bay | homozygote | Early adult | 2.15x10-9 | ||
| abnormal bone structure | 1 supporting dataset | Gdf5em1(IMPC)H | homozygote | Early adult | 4.41x10-7 | ||
| abnormal digit morphology | 4 supporting datasets | Gdf5em1(IMPC)H | homozygote | Early adult | 1.1x10-23 | ||
| limb grasping | 1 supporting dataset | Gdf5em1(IMPC)H | homozygote | Early adult | 1.91x10-8 | ||
| abnormal autopod morphology | 4 supporting datasets | Gdf5em1(IMPC)H | homozygote | Early adult | 1.1x10-23 | ||
| decreased locomotor activity | 2 supporting datasets | Gdf5em1(IMPC)H | homozygote | Early adult | 1.52x10-5 | ||
| increased bone mineral density | 1 supporting dataset | Gdf5em1(IMPC)H | homozygote | Early adult | 5.11x10-5 |
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External links
No external links available for Gdf5.
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