Gabrr2 | gamma-aminobutyric acid type A receptor subunit rho 2
GeneMGI:95626
Physiological systems
21 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland
19 No significant impact
3 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| small testis | 1 supporting dataset | Gabrr2tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal testis morphology | 1 supporting dataset | Gabrr2tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/1) | 0.19% (1/533) |
| blood | heterozygote | n/a | 0% (0/2) | 0% (0/17) |
| bone marrow | heterozygote | n/a | 0% (0/2) | 0% (0/22) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | n/a | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/2) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
Human diseases caused by Gabrr2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Gabrr2.
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| Gabrr2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Gabrr2tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Gabrr2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Gabrr2tm35935(L1L2_st0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |