Flnc | filamin C, gamma
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Cardiovascular system Mortality/aging
16 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased body temperature | 1 supporting dataset | Flncem1(IMPC)Bay | heterozygote | Early adult | 5.17x10-5 | ||
| abnormal heart looping | 1 supporting dataset | Flncem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Flncem1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal somite shape | 1 supporting dataset | Flncem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Flncem1(IMPC)Bay | homozygote | E12.5 | N/A * | ||
| abnormal vitelline vasculature morphology | 1 supporting dataset | Flncem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Flncem1(IMPC)Bay | homozygote | E9.5 | N/A * |
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External links
No external links available for Flnc.
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| Flncem1(IMPC)Bay | Exon Deletion | | mouse |
| Flnctm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Flnctm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |