Fgfr1 | fibroblast growth factor receptor 1
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
24Associated diseases
Expression examined in:41Adult tissues
30Embryo tissues
| abnormal embryo size | 1 supporting dataset | Fgfr1tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Fgfr1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Fgfr1tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| increased respiratory quotient | 1 supporting dataset | Fgfr1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.89x10-5 | ||
| embryonic growth retardation | 1 supporting dataset | Fgfr1tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * |
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External links
No external links available for Fgfr1.
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| Fgfr1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell mouse |
| Fgfr1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Fgfr1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Fgfr1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |
| Fgfr1tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Fgfr1tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |