Mecom | MDS1 and EVI1 complex locus
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Mortality/aging
16 No significant impact
2 Not tested
Data collections
Gene metrics:12Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased prepulse inhibition | 4 supporting datasets | MecomJbo | heterozygote | Early adult | 1.85x10-7 | ||
| thrombocytopenia | 1 supporting dataset | Mecomem1(IMPC)J | heterozygote | Early adult | 2.72x10-10 | ||
| decreased hemoglobin content | 2 supporting datasets | MecomJbo | heterozygote | Early adult | 1.61x10-12 | ||
| increased startle reflex | 3 supporting datasets | MecomJbo | heterozygote | Early adult | 2.56x10-11 | ||
| decreased erythrocyte cell number | 1 supporting dataset | MecomJbo | heterozygote | Early adult | 7.77x10-6 | ||
| increased circulating amylase level | 1 supporting dataset | MecomJbo | heterozygote | Early adult | 1.47x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Mecomem1(IMPC)J | homozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | MecomJbo | homozygote | Early adult | N/A * | ||
| increased lean body mass | 1 supporting dataset | MecomJbo | heterozygote | Early adult | 5.49x10-10 | ||
| abnormal startle reflex | 1 supporting dataset | MecomJbo | heterozygote | Early adult | 3.6x10-7 |
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| Mecomem1(IMPC)J | Exon Deletion | | mouse |