Ephx1 | epoxide hydrolase 1, microsomal

GeneMGI:95405Synonyms: Eph-1, Eph1, +1 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex5 supporting datasetsEphx1Ephx1homozygoteEarly adult6.2x10-12 
increased mean corpuscular volume1 supporting datasetEphx1Ephx1homozygoteEarly adult5.24x10-5 
increased IgA level1 supporting datasetEphx1Ephx1homozygoteEarly adult1.04x10-5 
increased circulating potassium level1 supporting datasetEphx1Ephx1homozygoteEarly adult6.77x10-5 
decreased erythrocyte cell number1 supporting datasetEphx1Ephx1homozygoteEarly adult7.23x10-6 
thrombocytopenia1 supporting datasetEphx1Ephx1homozygoteEarly adult6.36x10-9 
decreased circulating triglyceride level1 supporting datasetEphx1Ephx1homozygoteEarly adult6.65x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ephx1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
mouse
Ephx1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Ephx1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Ephx1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Ephx1tm2e(EUCOMM)HmguTargeted, non-conditional allelees cell

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