Cyb5r3 | cytochrome b5 reductase 3

GeneMGI:94893Synonyms: 2500002N19Rik, 0610016L08Rik, +2 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



cataract	1 supporting dataset	Cyb5r3^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.64x10^-6
decreased fasting circulating glucose level	1 supporting dataset	Cyb5r3^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	7.32x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Cyb5r3^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cyb5r3.

Associated images

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Histopathology

There is no histopathology data found for Cyb5r3.

IMPC related publications

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External links

No external links available for Cyb5r3.

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*Cyb5r3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cyb5r3^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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