Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Physiological systems
17 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Behavior/neurological Skeleton Cardiovascular system Craniofacial
11 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:48Adult tissues
42Embryo tissues
| absent teeth | 1 supporting dataset | Slc6a3tm1b(KOMP)Wtsi | homozygote | Early adult | 5.63x10-7 | ||
| hyperactivity | 1 supporting dataset | Slc6a3tm1b(KOMP)Wtsi | heterozygote | Early adult | 4.95x10-9 | ||
| increased heart weight | 1 supporting dataset | Slc6a3tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.26x10-8 | ||
| increased circulating sodium level | 1 supporting dataset | Slc6a3tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.12x10-10 | ||
| abnormal tooth morphology | 1 supporting dataset | Slc6a3tm1b(KOMP)Wtsi | homozygote | Early adult | 3.38x10-6 | ||
| decreased circulating free fatty acids level | 1 supporting dataset | Slc6a3tm1b(KOMP)Wtsi | heterozygote | Early adult | 5.19x10-7 |
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External links
No external links available for Slc6a3.
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| Slc6a3tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Slc6a3tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Slc6a3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |