Ebf2 | early B cell factor 2

GeneMGI:894332Synonyms: Mmot1, O/E-3, +1 more

Physiological systems

22 / 24 physiological systems tested

16 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Hematopoietic system Craniofacial Cardiovascular system Renal/urinary system Homeostasis/metabolism Embryo Nervous system Vision/eye Liver/biliary system Behavior/neurological Mortality/aging

6 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:25Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal placenta morphology	1 supporting dataset	Ebf2^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
abnormal kidney morphology	1 supporting dataset	Ebf2^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal brain morphology	1 supporting dataset	Ebf2^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal facial morphology	1 supporting dataset	Ebf2^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Ebf2^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
abnormal skin morphology	1 supporting dataset	Ebf2^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Ebf2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Ebf2^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
enlarged spleen	1 supporting dataset	Ebf2^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
small spleen	1 supporting dataset	Ebf2^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ebf2.

Associated images

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Histopathology

There is no histopathology data found for Ebf2.

IMPC related publications

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External links

No external links available for Ebf2.

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*Ebf2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Ebf2^{tm88484(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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