Septin8 | septin 8

GeneMGI:894310Synonyms: Sept8, Sepl

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Hematopoietic system Behavior/neurological Skeleton

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased mean corpuscular volume	1 supporting dataset	Septin8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.58x10^-5
increased startle reflex	3 supporting datasets	Septin8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.07x10^-7
decreased bone mineral density	1 supporting dataset	Septin8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.67x10^-5
abnormal startle reflex	1 supporting dataset	Septin8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.35x10^-5
decreased prepulse inhibition	2 supporting datasets	Septin8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.92x10^-5
abnormal locomotor activation	1 supporting dataset	Septin8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.33x10^-5
increased circulating phosphate level	1 supporting dataset	Septin8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.67x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Septin8.

Associated images

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Histopathology

There is no histopathology data found for Septin8.

IMPC related publications

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External links

No external links available for Septin8.

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*Septin8^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Septin8^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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