Stx4a | syntaxin 4A (placental)
Physiological systems
15 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Mortality/aging
14 No significant impact
9 Not tested
Data collections
Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Stx4aem1(IMPC)H | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Stx4aem1(IMPC)H | homozygote | E9.5 | N/A * |
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Human diseases caused by Stx4a mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Stx4a.
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| Stx4aem1(IMPC)H | Exon Deletion | | mouse |
| Stx4atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Stx4atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |