Ctsd | cathepsin D
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Hematopoietic system Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased hematocrit | 1 supporting dataset | Ctsdtm1b(EUCOMM)Wtsi | heterozygote | Early adult | 6.65x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Ctsdtm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| cornea opacity | 1 supporting dataset | Ctsdtm1b(EUCOMM)Wtsi | heterozygote | Early adult | 7.35x10-5 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Ctsdtm1b(EUCOMM)Wtsi | heterozygote | Early adult | 4.48x10-11 |
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External links
No external links available for Ctsd.
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| Ctsdtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Ctsdtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Ctsdtm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ctsdtm41779(L1L2_st1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |