Anxa6 | annexin A6

GeneMGI:88255Synonyms: AnxVI, Anx6, +3 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Growth/size/body region Vision/eye Skeleton

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased bone mineral content	1 supporting dataset	Anxa6^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.13x10^-6
decreased circulating cholesterol level	1 supporting dataset	Anxa6^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.62x10^-5
increased lean body mass	1 supporting dataset	Anxa6^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.11x10^-5
decreased circulating LDL cholesterol level	1 supporting dataset	Anxa6^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.9x10^-5
abnormal eye size	1 supporting dataset	Anxa6^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.31x10^-6
abnormal vibrissa morphology	1 supporting dataset	Anxa6^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.88x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Anxa6.

Associated images

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Histopathology

There is no histopathology data found for Anxa6.

IMPC related publications

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External links

No external links available for Anxa6.

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*Anxa6^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Anxa6^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Anxa6^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Anxa6^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Anxa6^{tm350(pL1L2_GT0_bsd_frt15_neo_barcode)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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