Amelx | amelogenin, X-linked

GeneMGI:88005Synonyms: Rgsc888, Amg, +2 more

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Respiratory system Hematopoietic system Skeleton Craniofacial Cardiovascular system

11 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:24Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal thymus morphology	1 supporting dataset	Amelx^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Amelx^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Amelx^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged stomach	1 supporting dataset	Amelx^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
vertebral transformation	1 supporting dataset	Amelx^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.55x10^-6
abnormal tooth morphology	3 supporting datasets	Amelx^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Amelx^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*
abnormal tooth morphology	2 supporting datasets	Amelx^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small spleen	1 supporting dataset	Amelx^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Amelx^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Amelx.

Associated images

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Histopathology

There is no histopathology data found for Amelx.

IMPC related publications

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External links

No external links available for Amelx.

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*Amelx^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Amelx^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Amelx^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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