Cpgi5563 | CpG island 5563

GeneMGI:5670665Synonyms: CGI5563

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Mortality/aging

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adultN/A * 
increased lean body mass1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adult1.57x10-7 
increased circulating chloride level1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adult2.51x10-5 
decreased circulating triglyceride level1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adult7.46x10-10 
decreased circulating glucose level1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adult4.47x10-5 
decreased circulating cholesterol level1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adult6.44x10-15 
decreased fasting circulating glucose level1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adult1.3x10-6 
decreased circulating glycerol level1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adult1.54x10-9 
decreased circulating LDL cholesterol level1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adult2.86x10-7 
increased circulating magnesium level1 supporting datasetCpgi5563tm1.1(NCC)WCShomozygoteEarly adult5.46x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cpgi5563tm1(NCC)WCSReporter-tagged deletion allele (with selection cassette)es cell
mouse
Cpgi5563tm1(NCC)WCSKO first allele (reporter-tagged insertion with conditional potential)targeting vector
Cpgi5563tm1.1(NCC)WCSReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Cpgi5563tm1000451(L1L2_lncRNA_xpA3_BactNeo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Cpgi5563tm1000462(L1L2_lncRNA_xpA3_BactNeo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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