Cpgi5563 | CpG island 5563
Physiological systems
16 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Mortality/aging
12 No significant impact
8 Not tested
Data collections
Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
preweaning lethality, incomplete penetrance | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | N/A * | ||
increased lean body mass | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | 1.57x10-7 | ||
increased circulating chloride level | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | 2.51x10-5 | ||
decreased circulating triglyceride level | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | 7.46x10-10 | ||
decreased circulating glucose level | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | 4.47x10-5 | ||
decreased circulating cholesterol level | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | 6.44x10-15 | ||
decreased fasting circulating glucose level | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | 1.3x10-6 | ||
decreased circulating glycerol level | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | 1.54x10-9 | ||
decreased circulating LDL cholesterol level | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | 2.86x10-7 | ||
increased circulating magnesium level | 1 supporting dataset | Cpgi5563tm1.1(NCC)WCS | homozygote | Early adult | 5.46x10-8 |
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Human diseases caused by Cpgi5563 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Cpgi5563.
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Cpgi5563tm1(NCC)WCS | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Cpgi5563tm1(NCC)WCS | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Cpgi5563tm1.1(NCC)WCS | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Cpgi5563tm1000451(L1L2_lncRNA_xpA3_BactNeo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Cpgi5563tm1000462(L1L2_lncRNA_xpA3_BactNeo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |