Nhsl2 | NHS like 2
Physiological systems
18 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Reproductive system Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system
11 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| thick skin | 1 supporting dataset | Nhsl2em1(IMPC)Tcp | hemizygote | Early adult | N/A * | ||
| enlarged urinary bladder | 1 supporting dataset | Nhsl2em1(IMPC)Tcp | hemizygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Nhsl2em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Nhsl2em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Nhsl2em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Nhsl2em1(IMPC)Tcp | hemizygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Nhsl2em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Nhsl2em1(IMPC)Tcp | hemizygote | Early adult | N/A * | ||
| small uterus | 1 supporting dataset | Nhsl2em1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Nhsl2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Nhsl2.
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| Nhsl2em1(IMPC)Tcp | Inter-exon deletion | | mouse |
| Nhsl2tm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Nhsl2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Nhsl2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |