Prdm14 | PR domain containing 14
GeneMGI:3588194
Physiological systems
19 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological Skeleton Mortality/aging
8 No significant impact
5 Not tested
Data collections
Gene metrics:19Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
0Embryo tissues
| abnormal bone structure | 1 supporting dataset | Prdm14em1(IMPC)Bay | homozygote | Early adult | 3.99x10-5 | ||
| decreased lean body mass | 2 supporting datasets | Prdm14em1(IMPC)Bay | homozygote | Early adult | 1.43x10-7 | ||
| female infertility | 1 supporting dataset | Prdm14tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| decreased bone mineral content | 2 supporting datasets | Prdm14tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.19x10-18 | ||
| decreased lean body mass | 1 supporting dataset | Prdm14tm1b(EUCOMM)Wtsi | homozygote | Early adult | 5.75x10-5 | ||
| abnormal eye anterior chamber depth | 1 supporting dataset | Prdm14em1(IMPC)Bay | homozygote | Early adult | 7.94x10-9 | ||
| abnormal bone structure | 1 supporting dataset | Prdm14tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.26x10-7 | ||
| decreased bone mineral content | 2 supporting datasets | Prdm14em1(IMPC)Bay | homozygote | Early adult | 1.75x10-11 | ||
| short tibia | 1 supporting dataset | Prdm14tm1a(EUCOMM)Wtsi | homozygote | Early adult | 6.46x10-9 | ||
| male infertility | 1 supporting dataset | Prdm14tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/4) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/4) | 0.19% (1/533) |
| bone | heterozygote | n/a | 0% (0/4) | 0% (0/394) |
| brain | heterozygote | n/a | 0% (0/4) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 0% (0/4) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/4) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/4) | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/4) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 0% (0/4) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 0% (0/4) | 0.41% (2/491) |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Prdm14.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Prdm14em1(IMPC)Bay | Exon Deletion | | mouse |
| Prdm14tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Prdm14tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Prdm14tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |