Rnase12 | ribonuclease, RNase A family, 12 (non-active)
GeneMGI:3528588
Physiological systems
20 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Immune system
19 No significant impact
4 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged lymph nodes | 1 supporting dataset | Rnase12em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Rnase12em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Rnase12 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Rnase12.
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| Rnase12em1(IMPC)Mbp | Whole-gene deletion | | mouse |
| Rnase12tm388929(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |