Slc2a12 | solute carrier family 2 (facilitated glucose transporter), member 12

GeneMGI:3052471Synonyms: Glut12, GLUT-12

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Cardiovascular system

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased heart left ventricle size1 supporting datasetSlc2a12em2(IMPC)BayhomozygoteEarly adult2.64x10-5 
thick ventricular wall1 supporting datasetSlc2a12em2(IMPC)BayhomozygoteEarly adult5.62x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Slc2a12 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Slc2a12em1(IMPC)Baymouse
Slc2a12em2(IMPC)BayExon Deletionmouse
Slc2a12tm360435(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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