Zfp300 | zinc finger protein 300
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Vision/eye Cardiovascular system
16 No significant impact
6 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased cardiac output | 1 supporting dataset | Zfp300em1(IMPC)Bay | homozygote | Early adult | 4.73x10-5 | ||
| abnormal eye posterior chamber depth | 1 supporting dataset | Zfp300em1(IMPC)Bay | hemizygote | Early adult | 2.62x10-5 |
| | | | | | | | | | |
Human diseases caused by Zfp300 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Zfp300.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Zfp300em1(IMPC)Bay | Exon Deletion | | mouse |
| Zfp300tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Zfp300tm88017(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |