4933430I17Rik | RIKEN cDNA 4933430I17 gene

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Endocrine/exocrine gland Muscle Limbs/digits/tail Hematopoietic system Skeleton Cardiovascular system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal pancreas morphology1 supporting dataset4933430I17Riktm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
short tibia1 supporting dataset4933430I17Riktm1b(EUCOMM)WtsihomozygoteEarly adult3.24x10-5 
increased cardiac muscle contractility1 supporting dataset4933430I17Riktm1b(EUCOMM)WtsihomozygoteEarly adult2.26x10-5 
increased circulating alanine transaminase level1 supporting dataset4933430I17Riktm1b(EUCOMM)WtsihomozygoteEarly adult2.26x10-11 
increased mean corpuscular volume1 supporting dataset4933430I17Riktm1a(EUCOMM)WtsihomozygoteEarly adult9.04x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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4933430I17Riktm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
4933430I17Riktm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
4933430I17Riktm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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