4933430I17Rik | RIKEN cDNA 4933430I17 gene
GeneMGI:3045314
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Endocrine/exocrine gland Muscle Limbs/digits/tail Hematopoietic system Skeleton Cardiovascular system
13 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal pancreas morphology | 1 supporting dataset | 4933430I17Riktm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| short tibia | 1 supporting dataset | 4933430I17Riktm1b(EUCOMM)Wtsi | homozygote | Early adult | 3.24x10-5 | ||
| increased cardiac muscle contractility | 1 supporting dataset | 4933430I17Riktm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.26x10-5 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | 4933430I17Riktm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.26x10-11 | ||
| increased mean corpuscular volume | 1 supporting dataset | 4933430I17Riktm1a(EUCOMM)Wtsi | homozygote | Early adult | 9.04x10-5 |
| | | | | | | | | | |
Human diseases caused by 4933430I17Rik mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for 4933430I17Rik.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| 4933430I17Riktm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| 4933430I17Riktm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| 4933430I17Riktm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |