Gsdma3 | gasdermin A3

GeneMGI:3044668Synonyms: Fgn, Bsk, +5 more

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Immune system Hematopoietic system

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased hematocrit	1 supporting dataset	Gsdma3^{tm1(KOMP)Vlcg}	homozygote	Early adult	2.4x10^-6
increased lymphocyte cell number	1 supporting dataset	Gsdma3^{tm1(KOMP)Vlcg}	homozygote	Early adult	8.31x10^-8
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Gsdma3^{tm1(KOMP)Vlcg}	homozygote	Early adult	1.91x10^-12
increased mean corpuscular hemoglobin	1 supporting dataset	Gsdma3^{tm1(KOMP)Vlcg}	homozygote	Early adult	1.37x10^-12
decreased erythrocyte cell number	1 supporting dataset	Gsdma3^{tm1(KOMP)Vlcg}	homozygote	Early adult	1.2x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gsdma3.

Associated images

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Histopathology

There is no histopathology data found for Gsdma3.

IMPC related publications

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External links

No external links available for Gsdma3.

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*Gsdma3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Gsdma3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gsdma3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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