Traf7 | TNF receptor-associated factor 7
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Immune system Vision/eye Mortality/aging
17 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| cataract | 1 supporting dataset | Traf7em1(IMPC)Tcp | heterozygote | Early adult | 7.25x10-7 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Traf7em1(IMPC)Tcp | homozygote | E12.5 | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Traf7em1(IMPC)Tcp | heterozygote | Early adult | 1.13x10-5 | ||
| enlarged lymph nodes | 1 supporting dataset | Traf7em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Traf7em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Traf7em1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| abnormal lens morphology | 1 supporting dataset | Traf7em1(IMPC)Tcp | heterozygote | Early adult | 3.03x10-5 |
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External links
No external links available for Traf7.
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| Traf7em1(IMPC)Tcp | Exon Deletion | | mouse |
| Traf7tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Traf7tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |