Fhip2b | FHF complex subunit HOOK interacting protein 2B
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Cardiovascular system
16 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal heart morphology | 1 supporting dataset | Fhip2bem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal thymus morphology | 1 supporting dataset | Fhip2bem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged thymus | 1 supporting dataset | Fhip2bem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged heart | 1 supporting dataset | Fhip2bem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Fhip2bem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Fhip2bem1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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Human diseases caused by Fhip2b mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Fhip2b.
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| Fhip2bem1(IMPC)Ccpcz | Exon Deletion | | mouse |
| Fhip2btm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |