Atxn7l3 | ataxin 7-like 3

GeneMGI:3036270Synonyms: E030022H21Rik

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Pigmentation Integument Limbs/digits/tail Vision/eye Behavior/neurological Skeleton Cardiovascular system Mortality/aging

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

short tibia2 supporting datasetsAtxn7l3tm1.1(KOMP)WtsiheterozygoteEarly adult1.33x10-7 
decreased total retina thickness1 supporting datasetAtxn7l3tm1.1(KOMP)WtsiheterozygoteEarly adult3.89x10-5 
abnormal retina vasculature morphology1 supporting datasetAtxn7l3tm1.1(KOMP)WtsiheterozygoteEarly adult4.22x10-9 
abnormal vocalization1 supporting datasetAtxn7l3tm1.1(KOMP)WtsiheterozygoteEarly adult2.45x10-5 
abnormal retina blood vessel morphology1 supporting datasetAtxn7l3tm1.1(KOMP)WtsiheterozygoteEarly adult4.18x10-9 
preweaning lethality, complete penetrance1 supporting datasetAtxn7l3tm1.1(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal coat/hair pigmentation1 supporting datasetAtxn7l3tm1.1(KOMP)WtsiheterozygoteEarly adult9.02x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atxn7l3tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
Atxn7l3tm1.1(KOMP)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Atxn7l3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)mouse
Atxn7l3tm210450(L1L2_Pgk_P)Reporter-tagged deletion allele (with selection cassette)targeting vector

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