Wee2 | WEE1 homolog 2 (S. pombe)

GeneMGI:3027899Synonyms: Wee1b, LOC381759

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Skeleton

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity2 supporting datasetsWee2em1(IMPC)JhomozygoteEarly adult3.85x10-5 
decreased bone mineral density1 supporting datasetWee2em1(IMPC)JhomozygoteEarly adult7.19x10-5 
decreased exploration in new environment1 supporting datasetWee2em1(IMPC)JhomozygoteEarly adult4.57x10-8 
decreased circulating iron level1 supporting datasetWee2em1(IMPC)JhomozygoteEarly adult3.6x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Wee2em1(IMPC)JIndelmouse
Wee2em2(IMPC)JDeletionmouse
Wee2em3(IMPC)JDeletionmouse
Wee2tm41904(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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