Cfap57 | cilia and flagella associated protein 57
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Reproductive system Muscle Nervous system
16 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| hydrocephaly | 2 supporting datasets | Cfap57em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal brain morphology | 2 supporting datasets | Cfap57em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal skeletal muscle morphology | 1 supporting dataset | Cfap57em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal spinal cord morphology | 1 supporting dataset | Cfap57em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| male infertility | 1 supporting dataset | Cfap57em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Cfap57 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Cfap57.
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| Cfap57em1(IMPC)Mbp | Exon Deletion | | mouse |
| Cfap57tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Cfap57tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Cfap57tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Cfap57tm478(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |