Cimap1d | CIMAP1 family member D

GeneMGI:2686003Synonyms: Odf3l2, LOC382384

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Integument Growth/size/body region Hearing/vestibular/ear Behavior/neurological Renal/urinary system

16 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

enlarged kidney1 supporting datasetCimap1dtm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
head bobbing1 supporting datasetCimap1dtm1.1(KOMP)VlcgheterozygoteEarly adult8.89x10-5 
abnormal gait1 supporting datasetCimap1dtm1.1(KOMP)VlcgheterozygoteEarly adult8.89x10-5 
abnormal kidney morphology1 supporting datasetCimap1dtm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
impaired righting response1 supporting datasetCimap1dtm1.1(KOMP)VlcgheterozygoteEarly adult8.89x10-5 
abnormal auditory brainstem response1 supporting datasetCimap1dtm1.1(KOMP)VlcghomozygoteEarly adult6.04x10-6 
absent vibrissae1 supporting datasetCimap1dtm1.1(KOMP)VlcgheterozygoteEarly adult1.29x10-6 
abnormal auditory brainstem response1 supporting datasetCimap1dtm1.1(KOMP)VlcgheterozygoteEarly adult2.22x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/2)0.7% (4/570)
aortaheterozygoten/a0% (0/2)0.19% (1/533)
bloodheterozygoten/a0% (0/1)0% (0/17)
bone marrowheterozygoten/a0% (0/2)0% (0/22)
brainheterozygoten/a0% (0/2)0.86% (5/579)
brainstemheterozygoten/an/a0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/an/a0.22% (1/454)
cecumheterozygoten/a0% (0/2)7.75% (22/284)
cerebellumheterozygoten/a0% (0/2)0.56% (3/532)
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Histopathology

IMPC related publications

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Cimap1dtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Cimap1dtm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Cimap1dtm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cimap1dtm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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