Prickle4 | prickle planar cell polarity protein 4

GeneMGI:2685785Synonyms: LOC381104

Physiological systems

15 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

13 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity2 supporting datasetsPrickle4em1(IMPC)MarchomozygoteEarly adult2.56x10-6 
decreased exploration in new environment1 supporting datasetPrickle4em1(IMPC)MarchomozygoteEarly adult1.42x10-5 
decreased circulating glucose level1 supporting datasetPrickle4em1(IMPC)MarchomozygoteEarly adult1.42x10-6 
increased circulating alanine transaminase level1 supporting datasetPrickle4em1(IMPC)MarchomozygoteEarly adult3.45x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prickle4em1(IMPC)MarcIndelmouse
Prickle4tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Prickle4tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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