Carmil2 | capping protein regulator and myosin 1 linker 2
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument
16 No significant impact
5 Not tested
Data collections
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating glucose level | 1 supporting dataset | Carmil2tm1b(KOMP)Mbp | homozygote | Early adult | 2.54x10-5 | ||
| abnormal coat/hair pigmentation | 3 supporting datasets | Carmil2tm1b(KOMP)Mbp | homozygote | Early adult | 1.63x10-11 | ||
| abnormal cholesterol homeostasis | 1 supporting dataset | Carmil2tm1b(KOMP)Mbp | homozygote | Early adult | 4.62x10-5 |
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Human diseases caused by Carmil2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Carmil2.
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| Carmil2tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Carmil2tm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Carmil2tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |