Atp13a3 | ATPase type 13A3

GeneMGI:2685387Synonyms: LOC224087, LOC385637, +1 more

Physiological systems

17 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

7 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:29Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina blood vessel morphology	1 supporting dataset	Atp13a3^em1(IMPC)J	homozygote	Early adult	1.01x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Atp13a3^em1(IMPC)J	homozygote	Early adult	1.74x10^-106
decreased locomotor activity	4 supporting datasets	Atp13a3^em1(IMPC)J	homozygote	Early adult	1.57x10^-11
decreased fasting circulating glucose level	1 supporting dataset	Atp13a3^em1(IMPC)J	homozygote	Early adult	4.3x10^-9
decreased circulating triglyceride level	1 supporting dataset	Atp13a3^em1(IMPC)J	homozygote	Early adult	2.27x10^-5
increased hematocrit	1 supporting dataset	Atp13a3^em1(IMPC)J	homozygote	Early adult	3.89x10^-46
decreased circulating glucose level	1 supporting dataset	Atp13a3^em1(IMPC)J	homozygote	Early adult	2.31x10^-16
improved glucose tolerance	2 supporting datasets	Atp13a3^em1(IMPC)J	homozygote	Early adult	2x10^-20
increased erythrocyte cell number	1 supporting dataset	Atp13a3^em1(IMPC)J	homozygote	Early adult	2.15x10^-35
decreased circulating total protein level	1 supporting dataset	Atp13a3^em1(IMPC)J	homozygote	Early adult	8.17x10^-35

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atp13a3.

Associated images

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Histopathology

There is no histopathology data found for Atp13a3.

IMPC related publications

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External links

No external links available for Atp13a3.

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*Atp13a3^em1(IMPC)J*	Exon Deletion	‌	mouse
*Atp13a3^em2H*	Point Mutation	‌	mouse
*Atp13a3^{tm46896(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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