Hspb6 | heat shock protein, alpha-crystallin-related, B6

GeneMGI:2685325Synonyms: Hsp20

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Skeleton Mortality/aging

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased mean corpuscular volume	1 supporting dataset	Hspb6^em1(IMPC)J	homozygote	Early adult	2.85x10^-12
decreased circulating cholesterol level	1 supporting dataset	Hspb6^em1(IMPC)J	homozygote	Early adult	4.33x10^-6
increased grip strength	4 supporting datasets	Hspb6^em1(IMPC)J	homozygote	Early adult	1.32x10^-6
thrombocytosis	1 supporting dataset	Hspb6^em1(IMPC)J	homozygote	Early adult	1.06x10^-6
decreased circulating HDL cholesterol level	1 supporting dataset	Hspb6^em1(IMPC)J	homozygote	Early adult	9.7x10^-7
increased bone mineral density	1 supporting dataset	Hspb6^em1(IMPC)J	homozygote	Early adult	3.51x10^-9
abnormal bone structure	1 supporting dataset	Hspb6^em1(IMPC)J	homozygote	Early adult	3.11x10^-6
increased bone mineral content	2 supporting datasets	Hspb6^em1(IMPC)J	homozygote	Early adult	3.84x10^-9
decreased erythrocyte cell number	1 supporting dataset	Hspb6^em1(IMPC)J	homozygote	Early adult	8x10^-9
decreased hemoglobin content	1 supporting dataset	Hspb6^em1(IMPC)J	homozygote	Early adult	3.32x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hspb6.

Associated images

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Histopathology

There is no histopathology data found for Hspb6.

IMPC related publications

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External links

No external links available for Hspb6.

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*Hspb6^em1(IMPC)J*	Exon Deletion	‌	mouse
*Hspb6^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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