Ffar3 | free fatty acid receptor 3

GeneMGI:2685324Synonyms: Gpr41, LOC233080

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Growth/size/body region Vision/eye Liver/biliary system Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetFfar3em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged kidney1 supporting datasetFfar3em1(IMPC)MbphomozygoteEarly adultN/A * 
small liver1 supporting datasetFfar3em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetFfar3em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetFfar3em1(IMPC)MbphomozygoteEarly adultN/A * 
microphthalmia1 supporting datasetFfar3em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Ffar3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Ffar3em1(IMPC)MbpWhole-gene deletionmouse
Ffar3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ffar3tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ffar3tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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