Prss47 | serine protease 47

GeneMGI:2685120Synonyms: LOC218304, Gm274

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Craniofacial

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal uterus morphology	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal tooth morphology	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
hydrometra	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal tooth color	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Prss47^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prss47.

Associated images

12 images

X-ray

XRay Images Forepaw

23 images

X-ray

XRay Images Hind Leg and Hip

11 images

X-ray

XRay Images Skull Dorso Ventral Orientation

11 images

X-ray

XRay Images Skull Lateral Orientation

22 images

X-ray

XRay Images Whole Body Dorso Ventral

11 images

X-ray

XRay Images Whole Body Lateral Orientation

Human diseases caused by Prss47 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.



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Histopathology

There is no histopathology data found for Prss47.

IMPC related publications

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External links

No external links available for Prss47.

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*Prss47^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse

My Genes

Prss47 | serine protease 47

Physiological systems

7 Significantly impacted by the knock-out

14 No significant impact

3 Not tested

Data collections

Phenotypes

lacZ Expression

Associated images

X-ray

X-ray

X-ray

X-ray

X-ray

X-ray

Human diseases caused by Prss47 mutations

Histopathology

IMPC related publications

External links

Order Mouse and ES Cells

The IMPC Newsletter

Access Data Release 22.1 Data