Klhl29 | kelch-like 29

GeneMGI:2683857Synonyms: A230106N14Rik, Kbtbd9

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Muscle Hematopoietic system Cardiovascular system Mortality/aging

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased respiratory quotient	1 supporting dataset	Klhl29^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.82x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Klhl29^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased cardiac muscle contractility	1 supporting dataset	Klhl29^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.26x10^-5
increased heart rate	1 supporting dataset	Klhl29^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.91x10^-8
prolonged QT interval	1 supporting dataset	Klhl29^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.12x10^-5
increased large unstained cell number	2 supporting datasets	Klhl29^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.43x10^-8
prolonged ST segment	1 supporting dataset	Klhl29^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.45x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Klhl29.

Associated images

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Histopathology

There is no histopathology data found for Klhl29.

IMPC related publications

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External links

No external links available for Klhl29.

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*Klhl29^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Klhl29^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Klhl29^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Klhl29^{tm79707(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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