Cspp1 | centrosome and spindle pole associated protein 1
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Behavior/neurological Skeleton
12 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal locomotor behavior | 1 supporting dataset | Cspp1em1(IMPC)J | homozygote | Early adult | 8.24x10-5 | ||
| abnormal vocalization | 1 supporting dataset | Cspp1em1(IMPC)J | homozygote | Early adult | 4.45x10-9 | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Cspp1em1(IMPC)J | homozygote | Early adult | 1.06x10-10 | ||
| decreased bone mineral content | 1 supporting dataset | Cspp1em1(IMPC)J | homozygote | Early adult | 2.69x10-5 | ||
| decreased circulating creatinine level | 1 supporting dataset | Cspp1em1(IMPC)J | homozygote | Early adult | 1.75x10-8 |
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Human diseases caused by Cspp1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Cspp1.
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| Cspp1em1(IMPC)J | Exon Deletion | | mouse |
| Cspp1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Cspp1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |