Mib2 | mindbomb E3 ubiquitin protein ligase 2

GeneMGI:2679684Synonyms: 2210008I11Rik, Zzank1

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Nervous system Vision/eye Behavior/neurological

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	2 supporting datasets	Mib2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.49x10^-6
abnormal retina morphology	4 supporting datasets	Mib2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.03x10^-5
decreased lean body mass	1 supporting dataset	Mib2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.06x10^-5
abnormal eye morphology	1 supporting dataset	Mib2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.87x10^-5
decreased blood urea nitrogen level	1 supporting dataset	Mib2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.47x10^-5
decreased prepulse inhibition	1 supporting dataset	Mib2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.63x10^-5
abnormal tail movements	1 supporting dataset	Mib2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.06x10^-7
decreased circulating amylase level	1 supporting dataset	Mib2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.47x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Mib2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Mib2.

IMPC related publications

Loading...

External links

No external links available for Mib2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Mib2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Mib2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mib2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Mib2^{tm44581(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes