Pyroxd1 | pyridine nucleotide-disulphide oxidoreductase domain 1

GeneMGI:2676395

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Digestive/alimentary Behavior/neurological Mortality/aging

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:49Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal stomach morphology	1 supporting dataset	Pyroxd1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
tremors	1 supporting dataset	Pyroxd1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.05x10^-7
preweaning lethality, complete penetrance	3 supporting datasets	Pyroxd1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Pyroxd1^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pyroxd1.

Associated images

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Histopathology

There is no histopathology data found for Pyroxd1.

IMPC related publications

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External links

No external links available for Pyroxd1.

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*Pyroxd1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pyroxd1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pyroxd1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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