Med13l | mediator complex subunit 13-like
Physiological systems
14 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Vision/eye Craniofacial Cardiovascular system
8 No significant impact
10 Not tested
Data collections
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal craniofacial morphology | 1 supporting dataset | Med13lem1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Med13lem1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal facial morphology | 1 supporting dataset | Med13lem1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| edema | 1 supporting dataset | Med13lem1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal blood vessel morphology | 1 supporting dataset | Med13lem1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| microphthalmia | 1 supporting dataset | Med13lem1(IMPC)Mbp | homozygote | E15.5 | N/A * |
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Human diseases caused by Med13l mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Med13l.
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| Med13lem1(IMPC)Mbp | Inter-exon deletion | | mouse |
| Med13ltm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Med13ltm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |