Mapk15 | mitogen-activated protein kinase 15

GeneMGI:2652894

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Hematopoietic system Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:

Life Stage:



decreased fasting circulating glucose level	1 supporting dataset	Mapk15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.91x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Mapk15^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	1.58x10^-6
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Mapk15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.33x10^-6
hyperactivity	2 supporting datasets	Mapk15^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	3.75x10^-7
decreased locomotor activity	1 supporting dataset	Mapk15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.34x10^-6
abnormal startle reflex	1 supporting dataset	Mapk15^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	3.31x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mapk15.

Associated images

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Histopathology

There is no histopathology data found for Mapk15.

IMPC related publications

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External links

No external links available for Mapk15.

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*Mapk15^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mapk15^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mapk15^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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