Baiap2l2 | BAI1-associated protein 2-like 2
GeneMGI:2652819
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Muscle Hearing/vestibular/ear Nervous system Hematopoietic system Behavior/neurological Cardiovascular system
12 No significant impact
5 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating bilirubin level | 1 supporting dataset | Baiap2l2tm1a(EUCOMM)Hmgu | homozygote | Early adult | 3.86x10-5 | ||
| abnormal startle reflex | 1 supporting dataset | Baiap2l2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.24x10-15 | ||
| abnormal auditory brainstem response | 4 supporting datasets | Baiap2l2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.58x10-24 | ||
| increased cardiac muscle contractility | 1 supporting dataset | Baiap2l2tm1a(EUCOMM)Hmgu | homozygote | Early adult | 4.75x10-7 | ||
| decreased prepulse inhibition | 5 supporting datasets | Baiap2l2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.74x10-13 | ||
| abnormal auditory brainstem response | 5 supporting datasets | Baiap2l2tm1a(EUCOMM)Hmgu | homozygote | Early adult | 5.25x10-10 | ||
| decreased startle reflex | 1 supporting dataset | Baiap2l2tm1a(EUCOMM)Hmgu | homozygote | Early adult | 8.69x10-8 | ||
| decreased grip strength | 2 supporting datasets | Baiap2l2tm1a(EUCOMM)Hmgu | homozygote | Early adult | 2.54x10-5 | ||
| abnormal gait | 1 supporting dataset | Baiap2l2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 7.32x10-5 | ||
| decreased hematocrit | 1 supporting dataset | Baiap2l2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.61x10-5 |
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Human diseases caused by Baiap2l2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Baiap2l2.
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| Baiap2l2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Baiap2l2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Baiap2l2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Baiap2l2tm83489(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |