Nr1d2 | nuclear receptor subfamily 1, group D, member 2
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Vision/eye Hematopoietic system Behavior/neurological
17 No significant impact
2 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating alanine transaminase level | 1 supporting dataset | Nr1d2em1(IMPC)Mbp | homozygote | Early adult | 4.13x10-5 | ||
| decreased T cell number | 1 supporting dataset | Nr1d2tm1Dgen | homozygote | Early adult | 8.21x10-8 | ||
| abnormal lens morphology | 1 supporting dataset | Nr1d2tm1Dgen | homozygote | Early adult | 5.01x10-6 | ||
| abnormal locomotor activation | 1 supporting dataset | Nr1d2tm1Dgen | homozygote | Early adult | 7.01x10-6 | ||
| abnormal eye morphology | 1 supporting dataset | Nr1d2tm1Dgen | homozygote | Early adult | 9.69x10-8 | ||
| decreased CD8-positive, alpha-beta T cell number | 1 supporting dataset | Nr1d2tm1Dgen | homozygote | Early adult | 4.92x10-9 | ||
| cataract | 1 supporting dataset | Nr1d2tm1Dgen | homozygote | Early adult | 5.01x10-6 | ||
| abnormal pupil morphology | 1 supporting dataset | Nr1d2tm1Dgen | homozygote | Early adult | 3.65x10-5 | ||
| increased B cell number | 1 supporting dataset | Nr1d2tm1Dgen | homozygote | Early adult | 5.52x10-7 | ||
| abnormal iris morphology | 1 supporting dataset | Nr1d2tm1Dgen | homozygote | Early adult | 3.35x10-7 |
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External links
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| Nr1d2em1(IMPC)Mbp | Indel | | mouse |