Pi4ka | phosphatidylinositol 4-kinase alpha
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Immune system Hematopoietic system Behavior/neurological Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
6Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues
| increased erythrocyte cell number | 1 supporting dataset | Pi4katm1b(EUCOMM)Wtsi | heterozygote | Early adult | 5.84x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Pi4katm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased hematocrit | 1 supporting dataset | Pi4katm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.99x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Pi4katm1b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
| increased monocyte cell number | 1 supporting dataset | Pi4katm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2x10-10 | ||
| limb grasping | 1 supporting dataset | Pi4katm1b(EUCOMM)Wtsi | heterozygote | Early adult | 9.29x10-6 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Pi4katm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * |
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External links
No external links available for Pi4ka.
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| Pi4katm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Pi4katm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pi4katm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |