Sbsn | suprabasin
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Skeleton Cardiovascular system
18 No significant impact
3 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased heart atrium size | 1 supporting dataset | Sbsnem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| increased circulating creatine kinase level | 1 supporting dataset | Sbsnem1(IMPC)Ccpcz | homozygote | Early adult | 3.14x10-10 | ||
| increased circulating potassium level | 1 supporting dataset | Sbsnem1(IMPC)Ccpcz | homozygote | Early adult | 1.06x10-7 | ||
| abnormal joint morphology | 1 supporting dataset | Sbsnem1(IMPC)Ccpcz | homozygote | Early adult | 7.88x10-5 | ||
| abnormal heart morphology | 1 supporting dataset | Sbsnem1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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Human diseases caused by Sbsn mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Sbsn.
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