Sidt2 | SID1 transmembrane family, member 2

GeneMGI:2446134Synonyms: CGI-40

Physiological systems

15 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

13 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating amylase level1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult9.74x10-12 
increased circulating aspartate transaminase level1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult8.7x10-12 
decreased circulating cholesterol level1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult9.06x10-6 
decreased circulating total protein level1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult1.47x10-6 
decreased circulating glycerol level1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult5.68x10-6 
decreased circulating calcium level1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult1.51x10-7 
decreased circulating LDL cholesterol level1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult2.19x10-5 
thrombocytosis1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult8.05x10-6 
decreased circulating iron level1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult3.46x10-8 
decreased circulating HDL cholesterol level1 supporting datasetSidt2em1(IMPC)WtsihomozygoteEarly adult5.22x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sidt2em1(IMPC)WtsiExon Deletionmouse
Sidt2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Sidt2tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Sidt2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)es cell
mouse

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