Slc25a21 | solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21

GeneMGI:2445059Synonyms: 9930033G19Rik

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Craniofacial

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

1Associated diseases

Expression examined in:90Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



abnormal snout morphology	1 supporting dataset	Slc25a21^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.34x10^-13
abnormal mandible morphology	1 supporting dataset	Slc25a21^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.73x10^-8
abnormal joint morphology	1 supporting dataset	Slc25a21^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.64x10^-14
decreased body weight	5 supporting datasets	Slc25a21^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.68x10^-11
decreased lean body mass	1 supporting dataset	Slc25a21^{tm1d(KOMP)Wtsi}	homozygote	Early adult	5.73x10^-5
abnormal cranium morphology	1 supporting dataset	Slc25a21^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.87x10^-12
decreased bone mineral content	1 supporting dataset	Slc25a21^{tm1d(KOMP)Wtsi}	homozygote	Early adult	6.24x10^-6
decreased mean corpuscular volume	1 supporting dataset	Slc25a21^{tm1d(KOMP)Wtsi}	homozygote	Early adult	1.16x10^-7
decreased bone mineral density	1 supporting dataset	Slc25a21^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.07x10^-6
decreased mean corpuscular hemoglobin	1 supporting dataset	Slc25a21^{tm1d(KOMP)Wtsi}	homozygote	Early adult	2.59x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc25a21.

Associated images

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Histopathology

There is no histopathology data found for Slc25a21.

IMPC related publications

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External links

No external links available for Slc25a21.

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*Slc25a21^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Slc25a21^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Slc25a21^{tm1c(KOMP)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Slc25a21^{tm1d(KOMP)Wtsi}*	Deletion allele (post-Flp and Cre with no reporter)	‌	mouse
*Slc25a21^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Slc25a21^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Slc25a21^{tm41920(L1L2_Pgk_PM)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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