Trappc11 | trafficking protein particle complex 11
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hearing/vestibular/ear Mortality/aging
15 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Trappc11em1(IMPC)J | homozygote | E9.5 | N/A * | ||
| increased circulating creatinine level | 1 supporting dataset | Trappc11em1(IMPC)J | heterozygote | Early adult | 6.41x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Trappc11em1(IMPC)J | homozygote | Early adult | N/A * |
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Human diseases caused by Trappc11 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Trappc11.
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| Trappc11em1(IMPC)J | Exon Deletion | | mouse |