Nemp2 | nuclear envelope integral membrane protein 2
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Integument Nervous system Hematopoietic system Behavior/neurological
12 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal spleen morphology | 1 supporting dataset | Nemp2em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased prepulse inhibition | 1 supporting dataset | Nemp2em1(IMPC)Tcp | homozygote | Early adult | 6.79x10-6 | ||
| decreased exploration in new environment | 1 supporting dataset | Nemp2em1(IMPC)Tcp | homozygote | Early adult | 6.95x10-8 | ||
| abnormal skin morphology | 1 supporting dataset | Nemp2em1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Nemp2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Nemp2.
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| Nemp2em1(IMPC)Tcp | Exon Deletion | | mouse |
| Nemp2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Nemp2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |