Nell1 | NEL-like 1
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Vision/eye Hematopoietic system Renal/urinary system
15 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small adrenal glands | 1 supporting dataset | Nell1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Nell1em1(IMPC)Mbp | homozygote | Early adult | 9.23x10-5 | ||
| abnormal vitreous body morphology | 1 supporting dataset | Nell1em1(IMPC)Mbp | homozygote | Early adult | 7.3x10-5 | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Nell1em1(IMPC)Mbp | homozygote | Early adult | 3.65x10-7 | ||
| abnormal lymph node morphology | 1 supporting dataset | Nell1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Nell1em1(IMPC)Mbp | homozygote | Early adult | 5.3x10-5 | ||
| small kidney | 1 supporting dataset | Nell1em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Nell1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Nell1.
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| Nell1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Nell1tm43045(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Nell1tm43045(L1L2_st0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |